San Luis Obispo Population 2025. San luis obispo city, california. The population development of the places in san luis obispo.
The population of san luis obispo is 47,402, with a population density of 3,563 people per square mile, diverging from the national average of 91. This page reports on the population distribution in san luis obispo, both in terms of raw head counts, and in terms of population density per square mile.